Coagulation Factor V; Human Plasma

Code: 219365-100UG D2-231

Analysis Note

Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma

General description

Nat...


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€1,220.00 100UG
€1,500.60 inc. VAT

Analysis Note

Clotting activity is determined by comparison to a standard curve produced using normal pooled human plasma

General description

Native coagulation factor V from human plasma. Thrombin cleaves Factor V to yield activated Factor Va, which exhibits 50-fold greater activity than the precursor molecule. Factor Va, Ca2+, and membrane phospholipids are cofactors which form a "prothrombinase" complex with Factor Xa, enabling its proteolytic activation of prothrombin to thrombin.

Native coagulation factor V from human plasma. Thrombin cleaves Factor V to yield activated Factor Va, which exhibits 50-fold greater activity than the precursor molecule. Factor Va, Ca2+, and membrane phospholipids are cofactors that form a "prothrombinase" complex with Factor X, enabling its proteolytic activation of prothrombin to thrombin.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Walker, F.J. 1992. J. Biol. Chem.267, 19896.Monkovic, D.D., and Tracy, P.B. 1990. J. Biol. Chem.265, 17132.Krishnaswamy, S., et al. 1989. J. Biol. Chem.264, 3160.Lee, C.D., and Mann, K.G. 1989. Blood73, 185.Krieg, U.C., et al. 1987. Biochemistry26, 103.

Packaging

100 µg in Plastic ampoule

Please refer to vial label for lot-specific concentration.

Physical form

In 50% glycerol/H2O (v/v).

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C). Do not store below -20°C.

Warning

Toxicity: Standard Handling (A)

assay≥95% (SDS-PAGE)
formliquid
manufacturer/tradenameCalbiochem®
Quality Level100
shipped inwet ice
specific activity≥20 units/mg protein (clotting assay)
storage conditionOK to freeze
storage temp.−20°C
Cas Number9001-24-5
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